AS Doukoure, M Keita, A Condé, M Traoré, A Kanté, M Diakité, B Kouakou
24-Jul-2025
Pediatric follicular lymphoma (PFCL) is a disease in which malignant B cells accumulate, crowd and cause lymphoid follicles to expand into the lymph nodes leading to lymphadenopathy. The disease accounts for 1.5% to 2% of all lymphomas that occur in the pediatric age group. We report the case of a 14-year-old male child who was a student received in August 2022 for exploration and management of bilateral cervical polylymphadenopathy evolving for more than 2 years, in whom clinical and paraclinical examination had revealed a WHO flipi II 2 grade 3 follicular lymphoma, without bulky or treatment criteria. Karyotype and FISH in search of t(14; 18) and BCL2 mutation were not performed. PFL accounts for 1.5% to 2% of all lymphomas that occur in the predominantly male pediatric age group. In our case, the age of the patient is 14 years old, male, as described in the literature. The clinical manifestations of PFL are dominated by lymphadenopathy in the cervical regions and, less commonly, in the axillary and inguinal. In our case, the location of the lymphadenopathy was cervical, bilateral, coelomensenteric and paraaortic. Pediatric follicular lymphoma (PFL) remains a rare entity of follicular lymphomas, histology is most often at WHO stage three (3) and in terms of prognosis and therapeutically the prognosis remains favorable with chemotherapy.
Lymphoma, Follicular, Pediatric, Abidjan