Résumé

Immune thrombocytopenic purpura is a rare autoimmune hemorrhagic pathology. It’s association with pregnancy is also rare. The management of immune thrombocytopenic purpura in pregnancy can be a challenge in limited resource setting. We report the prenatal monitoring and delivery management of a patient with a severe form of immune thrombocytopenic purpura that became resistant to prednisone. The diagnosis was made at the 28th week of amenorrhea during a previous pregnancy. During this new pregnancy, severe biological signs appeared at 7th week of amenorrhea despite prednisone therapy. Betamethasone administered for fetal lung maturation in the 3rd trimester of the pregnancy showed in the same time a platelet count rebound which improved maternal and perinatal prognosis. This case report aims to show the interest of Betamethasone in the management of refractory immune thrombocytopenic purpura in pregnancy as an alternative therapy to prednisone with low cost and helped to minimize heavy platelet transfusions and gamma globulin in the peripartum period.

Mot-clés :

Immune thrombocytopenic purpura, pregnancy, Betamethasone, Niger